Tablets & Capsules
is the only technical publication devoted to readers who formulate, manufacture, or package solid dosage forms.
Judged by the number of products on the market, tablets win hands down over capsules. But capsules offer more versatility in delivering drugs and dietary supplements. Here’s a glimpse at some of what’s new.
This article describes a study in which an enteric coating was applied to empty capsule shells to protect an insulin compound from the acidic environment of the stomach. The method enabled the compound to enter clinical trials quickly, saving time and money.
Terahertz spectroscopy is well suited to measure and control the density (solid fraction, porosity) of roller-compacted ribbons. In this article, the authors describe the principles of terahertz analysis and give examples of how it can help with formulation development and scale-up and commercialization of the roller compaction process.
Made from rice hulls, a processing byproduct, the flow agent can typically be used as a one-to-one replacement for silicon dioxide.
Using ACG’s Legacy 6100, operators “set the parameters, and the machine pretty much runs itself,” says the company’s VP of production operations.
Silica-based excipients perform a variety of functions and are available in a variety of types, grades, and uses. This column—the first in a two-part series—summarizes the chemical and physical properties, reactivity, regulatory status, pharmacology, toxicology, and applications of calcium silicate and metal oxide silicas.