Latest FocusUnderstanding maximum compression force(Free)Manufacturing a high-quality tablet punch starts with high-quality tool steel, and the tabletting industry uses many different types. This article discusses how computer modeling helps determine the maximum compression force tablet tooling can withstand.Assessing the performance of a co-processed HPMC-lactose excipient using an instrumented tablet pressThis article describes a study that assessed the performance of a lactose-HPMC co-processed excipient in the manufacture of modified-release tablets using a direct-compression blend and an instrumented tablet press. Ibuprofen was used as the model API.The advantages of alternative solid dosage formsWhile tablets and capsules have long been the go-to option, a poll conducted last year shows many people have difficulty swallowing them. That can lead to poor compliance. This article describes how alternatives to traditional solid dosage forms can improve compliance and provide companies with a competitive advantage.General FeaturesEye on Excipients: Functionalized calcium carbonateFunctionalized calcium carbonate is a structured mineral that serves as a multifunctional excipient. This edition of the column summarizes three studies of the substance that demonstrate applications in formulating tablets, orally disintegrating tablets, and orally disintegrating granules.
Back Page: Excipient variability: Mostly a fuss(Free)Excipients do cause batch failures. But we need to ask: How often are they the culprit and can we elucidate what role excipient variability plays in this manufacturing fact of life?