Tablets and Capsules Monday, September 06, 2010
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Tablets & Capsules is the only technical publication devoted exclusively to readers in the tablet and capsule processing industries.
 

ExcipientFest: John A. McCarty
      Length: 4:26          Posted: 6/21/2010
John A. McCarty, a formulator with more than 30 years’ experience, discusses direct powder blends and co-processed excipients. McCarty is a Technical Advisor to Tablets & Capsules and founder of its "Eye on Excipients" column.

Video provided by Matthew Knopp, Tablets & Capsules


ExcipientFest: Janeen Skutnik
      Length: 7:17          Posted: 6/21/2010
Janeen Skutnik, chair of IPEC-Americas and director of quality and regulatory policy at Pfizer, outlines the success of IPEC’s collaboration with ExcipientFest. She also describes plans for the FDA to use IPEC’s GMP documents to establish regulatory standards for pharmaceutical excipients.

Video provided by Matthew Knopp, Tablets & Capsules

ExcipientFest: Irwin B. Silverstein      Length: 5:39          Posted: 6/21/2010
Irwin Silverstein, chief operating officer of International Pharmaceutical Excipients Auditing (IPEA), describes the importance of the company’s ANSI accreditation for assessing GMP compliance. He also outlines how IPEA’s auditing program protects the confidentiality of excipient suppliers and pharmaceutical companies.

Video provided by Matthew Knopp, Tablets & Capsules

Xcelolab micro-dosing system      Length: 3:52          Posted: 4/20/2010
David Edwards of Capsugel demonstrates a lab-sized version of the company’s micro-dosing system. It operates on the same tapping principle, dispensing as little as 100 micrograms of powder into vials and other containers. The system was on display at the AAPS annual meeting in Los Angeles in November.

Video provided by Matthew Knopp, Tablets & Capsules

Swallowing a banana   Length: 0:04   Posted: 4/7/2010
Ultrasound imaging of the throat shows a subject swallowing chewed banana with ease. See "Seeds of change: Thoughts on making solid dosage forms easier to swallow" in the April 2010 issue.

Video provided by Daniel Bar-Shalom, author of Seeds of change: Thoughts on making solid dosage forms easier to swallow

Swallowing a prune pit   Length: 0:01   Posted: 4/7/2010
Ultrasound imaging of the throat shows that the subject has no trouble swallowing a prune pit that weighs about 3 grams. See "Seeds of change: Thoughts on making solid dosage forms easier to swallow" in the April 2010 issue.

Video provided by Daniel Bar-Shalom, author of Seeds of change: Thoughts on making solid dosage forms easier to swallow

Swallowing an acetaminophen tablet   Length: 0:05   Posted: 4/7/2010
Ultrasound imaging of the throat shows that the subject who easily swallowed a 3-gram prune pit needed the force of a second swallow to pass a 0.5-gram acetaminophen tablet. See "Seeds of change: Thoughts on making solid dosage forms easier to swallow" in the April 2010 issue.

Video provided by Daniel Bar-Shalom, author of Seeds of change: Thoughts on making solid dosage forms easier to swallow

GMPC I Mini Coater tablet coating system   Length: 3:40   Posted: 2/5/2010
Matt Morganelli of Glatt Air Techniques describes the features of a self-contained benchtop film coating system, typically used for sub-kilogram batches. The system was on display at the 2009 AAPS annual meeting in Los Angeles.

Video provided by Matthew Knopp, Tablets & Capsules

ProSolv ODT excipient matrix     Length: 2:10       Posted: 2/5/2010
Ken Seufert of JRS Pharma introduces a co-processed excipient matrix at the 2009 AAPS annual meeting. The matrix speeds formulation of orally disintegrating tablets (ODTs), runs on standard equipment, and entails no royalty payments.

Video provided by Matthew Knopp, Tablets & Capsules

Capsule A Cracking      Length: 0:27          Posted: 1/10/2010
A two-piece hard gelatin capsule (Capsule A) filled with 100 percent dimethylacetamide (DMA) cracks spontaneously in areas of high tensile stress. DMA, a very hygroscopic material, causes the cracks to form quickly. Similar cracking appears more slowly in capsules filled with less aggressive materials, such as PEG 200 and PEG 400. See "Influence of mechanical stress on the formation of cracks in two-piece capsules" in the January 2010 issue.

Video provided by David Fulper, Haibo Wang, and Dawn Downey, authors of "Influence of mechanical stress on the formation of cracks in two-piece capsules."

Capsule B Cracking       Length: 2:15           Posted: 1/10/2010
A two-piece hard gelatin capsule (Capsule B) filled with 100 percent dimethylacetamide (DMA) cracks spontaneously in three areas: the bottom of the locking ring, the juncture of the locking ring and shoulder, and the area where the body rim contacts the cap shoulder. See "Influence of mechanical stress on the formation of cracks in two-piece capsules" in the January 2010 issue.

Video provided by David Fulper, Haibo Wang, and Dawn Downey, authors of "Influence of mechanical stress on the formation of cracks in two-piece capsules."



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