Natoli Engineering Corporate Profile

Natoli Engineering Corporate Profile

Natoli Engineering Corporate Profile

Natoli Engineering
Natoli Engineering
28 Research Park Circle
Saint Charles, MO 63304
United States
Phone: 636.926.8900
Website: www.natoli.com
The Global Leader in Tablet Compression Product Manufacturing. For more than 40 years, Natoli Engineering Company has provided tablet compression products and services including punches and dies, die table segments, tablet presses, tablet press replacement parts and turrets, press refurbishing services, tool inspection devices, tool management software, a Tablet Compression Accessories Catalog, technical training courses, technical support and troubleshooting, and laboratory services to the pharmaceutical, nutritional, can veterinary industries.

About Us

Natoli Engineering

WHO WE ARE:

Natoli Engineering is the global leader in the manufacturing of tablet compression tooling. Foundedon the uncompromising principle of providing the highest quality products to our clients.

Celebrating our 50th Anniversary, Natoli has advanced into a fully encompassing solutions provider in the oral solid dose industry by helping our clients establish processes to achieve the perfect tablet and capsule. This allows Natoli to deliver world class tablet compression tooling, best-in-class tablet presses, encapsulation machines, and replacement parts with exceptional global support.

Natoli remains committed to expanding innovation and industry leadership through science and technology. Natoli Scientific laboratories offer formulation development services to troubleshoot tablet manufacturing issues on a molecular level before they occur. Natoli has developed industry leading software, Natoli AIMTM analytical and control system software to provide essential data for R&D and large-scale production. Currently, Natoli offers TabletCAD®, a free web-based tablet design platform.

FACILITIES:

Natoli Engineering serves its clients with facilities on both U.S. coasts as well as in Europe. Our Midwest headquarters in St. Charles, MO is home to our administrative, manufacturing, refurbishing, training,and metallurgy facilities. Natoli Technical Centers in Long Island, NY; Southern California; and Szczecin, Poland, offer regional customer support with parts, accessories, tooling refurbishing, maintenance, and training. Natoli Scientific’s laboratory in Telford, PA, provides formulation evaluation, training, contract research, and consulting services.

MAJOR MARKETS:

Natoli serves the pharmaceutical, nutritional, veterinary, confectionary, and cannabis tableting and encapsulation markets around the world.

PRODUCTS AND SERVICES:

  • Tablet Compression Tooling
  • Tool and Tablet Design
  • Encapsulation Machines and Parts
  • Analytical and On-Site Consulting
  • Regional Technical Centers
  • Metallurgical Services 
  • Tablet  Presses
  • Tablet Replacement Parts
  • Technical Training
  • Tablet Press Refurbishing
  • Tablet Compression Accessories
  • Instrumentation and Software

 

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Natoli Engineering Corporate Profile

Natoli Engineering
Natoli Engineering
28 Research Park Circle
Saint Charles, MO 63304
United States
Phone: 636.926.8900
Website: www.natoli.com

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Featured Products

  • EZ Level

    February 10, 2026
    Quickly and accurately level your tablet press feeder with the Natoli EZ Level Feeder Base Leveling System. Improper leveling can cause excessive formulation loss and sever damage to your equipment. ... Read More
  • FastLok™ Die Table Surface

    January 07, 2026
    Don’t replace your turret—replace your surface! FastLok™ Die Table Surface from Natoli Engineering snaps in with patented quick-lock technology. Swap surfaces in minutes, slash downtime, and get back... Read More

Resources

  • Tamping: Fine-Tuning Capsule Filling

    October 04, 2022
    If you’re thinking about encapsulating high-volume, well- formulated products, a tamper-style encapsulator is your best bet (dosator-style encapsulators work with sticky products, while hand-filling-style machines handle coarse products and small volumes well) Tamper-style ... Read More
  • Tableting: Advantages of Using an Instrumented R&D Tablet Press

    September 19, 2019
    All tablet presses employ the same basic operating principle. They compact a formulation of granular or powdered ingredients within a die between two punches. At any scale, the tablet press applies significant mechanical loads to the formulation during manufacturing, and the ... Read More
  • Tablet Tooling: Maximize the Return on Your Tooling Investment with Proactive Maintenance

    July 12, 2018
    Tablet compression tooling is a significant investment. production costs compared to the cost of a tablet press or fluid-bed dryer, tablet manufacturers typically buy many sets of tooling over a drug product’s life cycle. Excessively worn or improperly maintained tooling can be a... Read More

News

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