Featured Articles

  • Solubility Solutions: Formulators Have a Growing Toolbox to Increase Uptake of OSDs

    When addressing solubility challenges, one size doesn’t fit all. Sixty to seventy percent of compounds in development are poorly water soluble (BCS II & IV) and as high as ninety percent for certain drug categories. Approaches to improve solubility and bioavailability of poorly soluble APIs include particle size reduction, complexation systems, lipid-based systems, and polymers & solid dispersions. Each approach has disadvantages, no one technology works on all components, and the number of ... read more

  • Managing Uncertainty: Mathematical Modeling Can Guide Key Tablet Coating Decisions

    The old saying that the only certainties in life are death and taxes is not quite true. The need for change is also a certainty in coated tablet manufacturing. Operations must adjust to varying conditions caused by changing markets, regulations, and business environments; improve production efficiency and competitiveness while ensuring and improving product quality; and modify operating conditions with minimum risk and production cost. read more

  • Making Waves

    One stone tossed into water creates many ripples. Sometimes those ripples reach farther and impact more things than the thrower initially intended or realized. Such is the case when the US Congress passed the Drug Quality and Security Act November 27, 2013. The intent was to protect consumers from counterfeit, stolen, contaminated, or harmful drugs. read more

  • Choosing the Best Imprinting Machine for your Pharmaceutical Product Identity

    Oral Solid Dosage Formulations (OSDF) bring progress with medicines that improve health and quality of life. The process to progress however, goes unseen by customers when they do not recognize your pharmaceutical product as the artwork it is. Every OSDF must be imprinted with an identifiable code by regulation, but is being identified enough after it all? read more
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