Driven by persistent supply chain disruptions, shifting trade dynamics, evolving customer expectations and the accelerating growth of the nutraceutical sector, the pharma ecosystem is rewiring where — and how — it operates.
Just as traveling salesmen once had to balance opportunity, risk and proximity to their customers, today’s pharmaceutical suppliers face similar pressures as they pursue the dream of the world’s largest pharma market.
Although not a routine manufacturing step, granulation plays a central role in determining the quality, consistency and performance of modern OSD products. This article explores how granulation can effectively underpin formulation to transform complex powder formulations into stable, scalable and bioavailable drugs.
Conventional drying will remain useful, but it does not have to set the limits of formulation. Lyophilization offers a way to reduce risk, protect value and build products that are ready today — and ready for the future.
Tablet delamination and capping are the most common tablet defects, causing costly production disruptions and lost batches.
Scaling up a tablet coating process from work performed with a small-scale unit to a full-scale production plant raises critical questions: Which controls and product attributes must remain unchanged, and which can or must be adjusted to meet product quality criteria and business objectives?