Avion Pharmaceuticals announced the commercial launch of DHIVY, the first and only carbidopa/levodopa (CD/LD) fractional tablet designed to be divided. Avion gained approval for DHIVY from the FDA in November 2021. This design enables more precise medication dosing and directly addresses a market need to assist in titration for the gold standard commonly used by those with Parkinson's Disease (PD), the fastest-growing neurological condition in the United States, for which there is currently no cure.
DHIVY was developed by two neurologists who recognized the need for a CD/LD tablet that could be easily individualized. The fractional tablet technology is designed with deep scores that enable patients to divide it precisely to match their recommended dose. Each tablet's four segments contain 6.25/25 mg of CD/LD—the smallest, precise dose available in today's market. The American Academy of Neurology (AAN) in its updated treatment guidelines for early Parkinson's disease recommends initiating patients with the lowest effective dose of immediate-release carbidopa/levodopa.