Articles in this Issue

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  Tableting: Minitablets and Microtip Tooling

  September 16, 2020
  Orally administered tablets are a popular pharmaceutical dosage form because they provide consistent dosing, ease of administration, low manufacturing costs, and long stability times. In recent years, minitablets have become an increasing portion of the tablet market. read more
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  Tableting: The Science Behind Sticking and How to Resolve It

  September 10, 2020
  Sticking is one of the most common problems tablet manufacturers encounter. Sticking describes the buildup of granules on the punch-tip face, which can be caused by several factors, including the formulation’s physicochemical properties and the surface characteristics of the punch face. Because ... read more
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  Water Activity and Moisture: The Complexity and Interrelationships Explained

  September 10, 2020
  Water is a critical factor for the physical and chemical stability of solid oral dosage formulations. It is necessary for the growth of microorganisms and can impact a formulation’s stickiness, caking, and structure. Water’s role in stability is in its potential to contribute to and participate in ... read more
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  Capsules: Gelatin supply disruptions threaten US pharmaceutical manufacturers

  September 10, 2020
  The US is a top spender on healthcare, but many of the drug products that Americans use are produced overseas. Both APIs and other materials, such as capsules, are often sourced from other countries and continents. read more
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  Analytical Techniques: Using Near-Infrared Spectroscopy and Chemometric Modeling to Simultaneously...

  September 10, 2020
  Near-infrared spectroscopy (NIR) has become more popular in the pharmaceutical industry in recent years as a rapid analytical tool for identifying raw materials and monitoring manufacturing processes. NIR allows optimal handling of specific and relevant information and is non-destructive and non-... read more
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  Eye on Excipients: Improving Adherence

  September 10, 2020
  Improving medication adherence is an important aspect of patient-focused pharmaceutical development. Typical approaches for improving adherence include changing the route of administration from intravenous to oral and reducing the dosing frequency. Orally disintegrating tablets (ODTs) are one of the... read more
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  Counterfeiters: Turn in or Turn Away?

  September 16, 2020
  Consumer product counterfeiting is a serious, worldwide problem. Everyday products, such as clothing, jewelry, cosmetics, and even cigarettes can be suspect. If it’s a successful brand, you can bet it will eventually be counterfeited. In most cases, buyers are unaware that they are purchasing a ... read more