Articles in this Issue

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  Tableting: Industry Perspectives on Sticking During Tablet Compression

  September 14, 2018
  Nearly every company that manufactures tablets has had to deal with a sticking problem during compression. Despite the problem’s ubiquitous nature, cross-functional collaborations to discuss sticking across the pharmaceutical industry have either ... read more
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  Tableting: Optimizing Your Tablet Press Tooling

  September 14, 2018
  Tablets come in many shapes and sizes, and tablet formulations have a range of physical characteristics and tableting properties, such as abrasiveness, corrosiveness, lubricity, and compressibility. With this in mind, it makes sense that a one-size-... read more
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  Capsule Filling: Solving Formulation Problems with Liquid-Filled Hard Capsules

  September 14, 2018
  Hard capsules have traditionally been filled with powders, but they can also be filled with non-aqueous liquids, suspensions, semisolids, thixotropic gels, self-emulsifying drug delivery systems (SEDDS), thermo-softened matrixes, and hot melts that ... read more
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  Softgels: Are Softgels Right for Your Product?

  September 14, 2018
  Softgels have been available since 1935 when Robert Pauli Scherer patented the rotary die encapsulation process. Since then, softgels have been used by the pharmaceutical industry for many applications, including the effective delivery of poorly ... read more
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  Eye on Excipients: How Moisture Content Affects Excipient Behavior

  September 14, 2018
  The moisture content of excipients plays an important role in the physical and chemical properties of pharmaceutical products. The characteristics of the excipients for a particular dosage of a formulation depend on their moisture sorption behavior, ... read more
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  Containing Hazardous Compounds in Tableting Operations

  September 14, 2018
  As pharmaceutical manufacturers develop and produce increasing numbers of highly potent active pharmaceutical ingredients (HPAPIs), they also must maintain worker safety. Depending on the level of safety required, companies must often make additional... read more