Articles in this Issue

• 

  Excipients Used for Solid Dosage: Innovations and Challenges

  June 01, 2024
  Solid dosage forms are cornerstones of pharmaceutical delivery systems. Their widespread preference among patients and healthcare providers is highlighted by their ease of administration, dosage accuracy, and cost-effectiveness. ... read more
• 

  Ready, Set, Action! How to Ensure the Rapid Onset of Action of Active Ingredients Administered...

  June 01, 2024
  For oral dosage forms, “onset of action” is defined as the duration of time between oral administration of the active ingredient, which can either be a drug or nutraceutical, and its therapeutic effects on the patient. It ... read more
• 

  A Recipe for Success: Mastering Tableting Requires Understanding Ingredient Attributes

  June 01, 2024
  Ask yourself, are you surviving batch to batch, or are you performing? It’s one thing to develop a batch that meets expectations at a small scale. It’s another to have ingredients perform well throughout the entire batch. ... read more
• 

  CAUTION: If You Don’t Schedule Time For Maintenance, Your Equipment Will Schedule It For You

  June 01, 2024
  Production is paramount in the fast-paced world of capsule manufacturing, which can make it difficult to schedule routine and preventative maintenance. But neglecting the maintenance of machines in an effort to maximize production... read more
• 

  Gummy Manufacturing

  June 01, 2024
  The gummy manufacturing industry is experiencing steady growth, driven by increasing consumer demand for convenient and enjoyable dietary supplements. Vitamin-fortified gummies dominated the market last year with nearly 24% share,... read more
• 

  Navigating Turret Bore Bushing Material Selection in Consideration of Difficult Formulations

  June 01, 2024
  When the bores in a tablet press turret wear, bushings are often the solution manufacturers turn to in order to avoid interruptions in production or the costs associated with a new replacement turret. Material selection for these ... read more
• 

  Requirements For the Use of Alternative Empty Hard Gelatin Capsule Suppliers for the Manufacture...

  June 01, 2024
  Two-piece empty hard gelatin capsules have long been a reliable oral drug delivery system. They are the preferred choice of many pharmaceutical products because they require fewer excipients than other drug formulations. In ... read more
• 

  How to Avoid Sticking and Picking in the Tableting Industry

  June 01, 2024
  Sticking is one of the most common issues for tablet manufacturers. It occurs when particles from the formulation adhere to the punch cup, resulting in defective tablets. Picking is a specific type of sticking that refers to ... read more
• 

  Five Questions to Ask When Choosing Low Nitrite Excipients as Part of Your Nitrosamine Mitigation...

  June 01, 2024
  Low nitrite excipients have emerged as a potential nitrosamine risk mitigation strategy for some formulations, especially when a vulnerable amine is present in the drug product. If deemed suitable, low nitrite excipients can offer... read more
• 

  Six Critical Checkpoints to Stay Compliant: Transparency Brings Greater Protection

  June 01, 2024
  The more you know about the people in your organization, the safer you are from risks that could damage your company, your reputation, or your compliance. The regulations in the pharmaceutical industry are understandably strict, ... read more
• 

  Getting More Active

  June 01, 2024
  Pharmaceutical excipients were once considered inert, inactive substances merely acting as vehicles or fillers for the active drug ingredients. However, this perception has shifted dramatically over time as research unveiled their... read more