Delves into all aspects of R&D and manufacturing of all oral solid dose (OSD) forms. Tracks industry trends. Relays latest applied research relevant to OSDs. Provides “how to” information for the latest techniques in formulation/excipients, tablet manufacturing, capsule filling and other aspects of the process—including logistics like supply-chain management.
Tablet compression tooling is a significant investment. production costs compared to the cost of a tablet press or fluid-bed dryer, tablet manufacturers typically buy many sets of tooling over a drug ...
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With today’s global pharmaceutical supply chain, setting United States Pharmacopeia–National Formulary (USP– NF) compendial specifications for excipients is becoming increasingly complicated. This is ...
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Orally disintegrating tablets (ODTs are not just another fancy dosage form; they address a very important component of treatment success: compliance. This is especially true for pediatric and ...
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Counterfeit drug products and their potentially fatal outcomes are in the news nearly every week. The market for counterfeit versions of drug products such as potency l pills and heparin is booming ...
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The US Drug Supply Chain Security Act (DSCSA) officially went into effect last November, and the European Union’s Falsified Medicines Directive (FMD) goes into effect in February 2019. While these ...
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Recent FDA regulations and guidances have simplified the notification procedure pharmaceutical companies must follow when making certain changes to equipment, technology, and processes. The agency now...
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With many grinding mills—including roller mills, rotor mills, hammer mills, air-classifier mills, and fluidized-bed opposed-jet mills—successfully achieving the desired production throughput depends ...
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Cetirizine dihydrochloride is a second-generation antihistamine that is used to treat hay fever, allergies, angioedema, and urticaria (hives). As an H1 antagonist, cetirizine relieves the symptoms of ...
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Bottles are one of the most common packaging forms for over-the-counter solid oral dosage medications and nutritional supplements. Tablets, capsules, and softgels are all commonly sold as bottled ...
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Film coating is a widely used process in tablet manufacturing. Applying a clear or colored aqueous or solvent-based coating can improve a pharmaceutical tablet’s appearance, taste, and/or ...
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A single-tube Coriolis flow meter is a cylindrical device that’s mounted inline on a tablet coating system’s solution supply tube. The flow meter monitors the coating solution flowrate and directly or...
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Although many effective pharmaceutical treatments exist, a recent Institute of Medicine report identified a gap between actual treatment success rates and those believed to be achievable. This gap has...
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Many dietary supplement products are manufactured by a contract manufacturer, packaged by a contract packager, tested by a contract laboratory, and distributed by a contract distributor. To ensure ...
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Pan coating is one of the oldest pharmaceutical solid oral dosage manufacturing processes. The process was created for adding a sugar coating to compressed tablets primarily to mask the tablets’ ...
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Many active pharmaceutical ingredients (APIs) can be formulated into either liquid or solid oral dosage forms. A major advantage of liquid dosage forms is that the API is already dissolved and ...
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