Delves into all aspects of R&D and manufacturing of all oral solid dose (OSD) forms. Tracks industry trends. Relays latest applied research relevant to OSDs. Provides “how to” information for the latest techniques in formulation/excipients, tablet manufacturing, capsule filling and other aspects of the process—including logistics like supply-chain management.
Capsules are perceived as elegant, easy to swallow dosage forms, widely used for delivery of nutraceutical and medicinal preparations. Advances in capsule technologies have hugely facilitated the ...
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Minitablets, defined as solid dosage forms with a diameter below or equal to 3 mm, have many benefits: they are easy to swallow, offer uniform release kinetics, and are easy on the gastrointestinal ...
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Pharma execs generally consider cosmetic tablet coating a less essential aspect of manufacturing because cosmetic coatings typically do not affect the drug delivery. Perhaps they should reconsider; ...
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To the average consumer, one gelatin capsule looks pretty much like any other— give or take minor differences in shape, size or color. But, to an expert, this couldn’t be further from the truth. The ...
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When it comes to mixing nutraceutical ingredients, not all blenders are created equal. Because there’s a wide range of particles in each “mix”—of different sizes and bulk densities—getting the right ...
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Pharmaceuticals that begin development based on powders or refined by powders include gels, ointments and suspensions, or tablet coatings. For these products, many different powders and powder ...
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According to its Wikipedia entry: “Deadliest Catch is an American reality television series that premiered on the Discovery Channel on April 12, 2005. The show follows crab fishermen aboard fishing ...
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The COVID-19 pandemic caused tremendous supply chain disruptions across practically every industry segment. The pharmaceutical industry was impacted by global trade restrictions as quarantine ...
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Pick up the annual report of any generic pharma company like Teva, Sandoz, Aurobindo Pharma, etc. and it will likely include claims about being an integrated pharma company. But really, what does “...
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Perhaps the problem goes back to prehistoric peoples struggling to get their daily grain out of a narrow-mouthed clay pot? Or maybe it began in the Industrial Revolution with the mechanizing of food ...
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Drug makers have traditionally employed continuous manufacturing for large volumes of a limited number of products. They also prefer direct compression when manufacturing solid dose products ...
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The nutra numbers don’t lie—the market for supplements is large and growing. For example, 1 out of 4 people worldwide take dietary supplements daily or almost every day,1 and about 77% of consumers ...
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Concerns about nitrosamines—which have been known to be carcinogenic since the 1950s—in pharmaceutical finished products (medicines) have been percolating for decades. Nitrosamines are not an ...
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The US Food and Drug Administration’s acronym for Corrective and Preventive Action (CAPA) can fi ll cGMP manufacturers with dread. Phrases like “death by CAPA” and “ineffective CAPA” are common in the...
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There’s no universally agreed definition of what constitutes a highly potent API (HPAPI). But a health-based exposure limit (HBEL) can serve as a more reliable indicator of whether an API is potent or...
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