Articles in this Issue

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  Dust Management: Monitoring Dust Collection Digitally Can Help Make Your Job Easier

  October 01, 2023
  Pharma manufacturing raises dust in many steps—in the handling of bulk materials, to milling, granulating, tableting, encapsulating, coating, and even packaging. And yet, if you work in maintenance, purchasing, or environmental ... read more
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  Hard to Handle: Switching from Manual to Automated Dispensing of Reactive Powders Improves...

  October 01, 2023
  Many chemical and pharmaceutical process engineers are challenged by metered dispensing of reactive powders into reactors and large tanks. But dispensing difficult to-handle ingredients in a contained and accurate method can be ... read more
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  Combustible Dust: Fire Prevention Strategies for Requirements Compliance

  October 01, 2023
  If you manufacture oral solid dosage drugs, your plant is likely full of a variety of bulk powders. Many of these powders are combustible, and if they accumulate, they can provide fuel for a devastating fire or explosion. For ... read more
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  An All-Purpose Vehicle for Heat-Free Processing Before Filling into Capsules

  October 01, 2023
  Capsules are perceived as elegant, easy to swallow dosage forms, widely used for delivery of nutraceutical and medicinal preparations. Advances in capsule technologies have hugely facilitated the incorporation of liquid, semi ... read more
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  Coating Conundrum: Grappling with Minitablet Film Coating Myths

  October 01, 2023
  Minitablets, defined as solid dosage forms with a diameter below or equal to 3 mm, have many benefits: they are easy to swallow, offer uniform release kinetics, and are easy on the gastrointestinal tract, among others. Taken ... read more
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  Cosmetic Coating: Saving Money by Employing a ‘Digital Twin’

  October 01, 2023
  Pharma execs generally consider cosmetic tablet coating a less essential aspect of manufacturing because cosmetic coatings typically do not affect the drug delivery. Perhaps they should reconsider; employing “digital twins” for ... read more
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  Keeping it Together: Tackling the Crosslinking Phenomenon in Gelatin Soft Capsules

  October 01, 2023
  To the average consumer, one gelatin capsule looks pretty much like any other— give or take minor differences in shape, size or color. But, to an expert, this couldn’t be further from the truth. The difference lies with the ... read more
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  Nutra Mixing Needs: Picking the Best Blender

  October 01, 2023
  When it comes to mixing nutraceutical ingredients, not all blenders are created equal. Because there’s a wide range of particles in each “mix”—of different sizes and bulk densities—getting the right result requires choosing the ... read more
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  Down to the Tiniest Particle

  October 01, 2023
  Pharmaceuticals that begin development based on powders or refined by powders include gels, ointments and suspensions, or tablet coatings. For these products, many different powders and powder mixtures are used. They usually ... read more
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  From The Editor: Deadliest Dust

  October 01, 2023
  According to its Wikipedia entry: “Deadliest Catch is an American reality television series that premiered on the Discovery Channel on April 12, 2005. The show follows crab fishermen aboard fishing vessels in the Bering Sea during... read more