Allows OSD industry leaders to provide instructions to sometimes intractable problems in OSD R&D and manufacturing. Invites OSD users to submit thorny problems for experts to help solve. Focuses on very specific issues in R&D and manufacturing. Covers all aspects of OSD manufacturing—including excipients, nutraceuticals, tableting, capsule filling, and logistics.
You have probably seen banding mentioned in a capsule manufacturer’s brochure, an ad, or discussed in trade journals. But, unless you’ve used it in your production, it’s hard to understand exactly what it is, and why you’d want to use it.
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Regardless of what you’re blending, there are consistent and historically proven fill level recommendations for all vessel shapes, be they double cone, slant or v-shape. While many blenders need to operate at the rated batch size, some have a batch size that deviates. Doublecheck with your vendor—...
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Ask an Expert: How can organizations improve manufacturing efficiency and reduce variability of pharmaceutical formulations in continuous manufacturing processes?
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Dwell time is the amount of time a tablet compression punch head flat is in contact with the compression roller of a rotary tablet press. The compression force applied when forming the tablet must be 90% above its peak value. Usually, the longer a product remains under peak compression, the greater...
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Consumer preference for softgel capsule technology to deliver pharmaceutical and nutraceutical products is growing fast -- primarily due to their consumer-preferred oral solid dose (OSD) form. Pill fatigue has boosted the popularity of consumer-friendly dosage forms including softgels, in alignment ...
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Most tablet coatings are solid suspensions or solutions, which may contain various ingredients such as natural or synthetic resins, polymers, gums, plasticizers, fillers, pigments, and flavors. Dispersing dry raw materials into liquid presents several processing challenges due to some powders' ...
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Film coating is undertaken for numerous reasons: improving the appearance of the tablet, protecting the tablet from light and moisture, to protect the stomach lining from aggressive formats and to control and engineer drug release.mIt is therefore vital that the tablet coating needs to be uniform, ...
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Modified, delayed, extended and sustained – controlled release oral dosage forms go by many names,
but how well do we as an industry actually know them? All ‘modified release’ formulations stand in
contrast to ‘immediate release’ formulations, but there are also nuances within the controlled ...
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