Delves into all aspects of R&D and manufacturing of all oral solid dose (OSD) forms. Tracks industry trends. Relays latest applied research relevant to OSDs. Provides “how to” information for the latest techniques in formulation/excipients, tablet manufacturing, capsule filling and other aspects of the process—including logistics like supply-chain management.
Oral solid dosage (OSD) forms make up a very large portion of the world’s drug delivery formats, and solid dose manufacturing increasingly takes the lion’s share of global outsourcing capacity, in the...
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Have you ever heard that less is more? While often used to describe art or architecture, the saying also works in the world of capsule filling.
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Raman spectroscopy is emerging as a powerful analytical tool for the pharmaceutical industry. Like the more common FTIR spectroscopy, Raman spectroscopy is part of the vibrational spectroscopy family ...
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The basics of rotary tablet compression tooling have stood the test of time.
However, the specifications of tooling design have become more sophisticated.
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Predicting operational performance is a complex task in any industry. For pharmaceutical manufacturers, the ability to keep critical assets online and provide uninterrupted operations can mean the ...
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Nutraceuticals production straddles the interface of food and pharmaceuticals manufacturing—two markets which themselves share plenty of overlap. Pharmaceutical customers often specify higher polish ...
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In some sections of the pharmaceutical industry, there appears to be a conflict between the advantages co-processed excipients can bring and the perceived increased regulatory burden they could cause.
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Package quality disputes between suppliers and customers often start with someone in the filling plant stating “these packages aren’t as good as the ones we ran last week” without any data to support ...
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Poor handling and aftercare procedures account for about 85% of punch-and-die problems. Cleaning reduces cross contamination—common tablet and tooling issues. It also enables an accurate assessment of...
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As I prepared to relaunch Tablets & Capsules with my CompareNetworks colleagues, I was reminded of the ancient Indian parable of the blind men and the elephant. Each touched a different part. The man ...
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There’s a cinematic subgenre I like to call “Everything’s connected”.
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Excipients are one of the anomalies of the pharmaceutical sciences. They are inactive; they are not intended to treat a disease or medical condition; yet, without excipients, the therapeutic advances ...
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When pharma companies consider making the switch from batch processing to continuous manufacturing (CM), they often first think about machinery. But they shouldn’t forget about formulation.
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The rise of continuous manufacturing in some industries heralded a paradigm shift for pharmaceutical production. However, batch production remains the standard for much of the industry.
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Call it the “oral paradox”: oral drug delivery dominates medicine administration because it is convenient and non-invasive. But that delivery often offers poor oral bioavailability. Developing more ...
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