Delves into all aspects of R&D and manufacturing of all oral solid dose (OSD) forms. Tracks industry trends. Relays latest applied research relevant to OSDs. Provides “how to” information for the latest techniques in formulation/excipients, tablet manufacturing, capsule filling and other aspects of the process—including logistics like supply-chain management.
More often than not, here in America our pills are no frills.
Unlike Europeans, the U.S. consumer is accustomed to seeing most medications packaged in bottles. In fact, an estimated 80% of all ...
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What’s driving sustainability in OSD packaging?
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Water is essential to life and empty capsules also have water (moisture). Moisture in empty gelatin and Hypromellose (HPMC) capsules are tested and controlled within certain limits to ensure quality, ...
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The distinction between the nutraceutical and pharmaceutical markets is not as stark as many assume. Representing two sides of the healthcare coin, the sectors approach the shared goal of improving ...
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Though the realm of that excipient industry has metamorphosed from conventional to intricate, Microcrystalline Cellulose (MCC) has explicitly been inevitable and most sought in pharmaceutical ...
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Is data integrity a new concept and does it only apply to drug manufacturers? The answer to both of those questions is “no”. Due to an increasingly complex supply chain, globalization, and the current...
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For more than a century, empty hard capsules have been a safe, effective dosage delivery system. However, half a century in, recognizing that although gelatin was ideal for hard capsules, it was not ...
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The use of mineral salts in food, nutritional and pharmaceutical formulations, while common practice, can present some difficulties in production of final dosage tablet and capsule applications.
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The COVID-19 pandemic caused tremendous supply chain disruptions across practically every industry segment. The pharmaceutical industry was impacted by global trade restrictions as quarantine ...
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Pick up the annual report of any generic pharma company like Teva, Sandoz, Aurobindo Pharma, etc. and it will likely include claims about being an integrated pharma company. But really, what does “...
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Perhaps the problem goes back to prehistoric peoples struggling to get their daily grain out of a narrow-mouthed clay pot? Or maybe it began in the Industrial Revolution with the mechanizing of food ...
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Drug makers have traditionally employed continuous manufacturing for large volumes of a limited number of products. They also prefer direct compression when manufacturing solid dose products ...
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The nutra numbers don’t lie—the market for supplements is large and growing. For example, 1 out of 4 people worldwide take dietary supplements daily or almost every day,1 and about 77% of consumers ...
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Concerns about nitrosamines—which have been known to be carcinogenic since the 1950s—in pharmaceutical finished products (medicines) have been percolating for decades. Nitrosamines are not an ...
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The US Food and Drug Administration’s acronym for Corrective and Preventive Action (CAPA) can fi ll cGMP manufacturers with dread. Phrases like “death by CAPA” and “ineffective CAPA” are common in the...
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