Delves into all aspects of R&D and manufacturing of all oral solid dose (OSD) forms. Tracks industry trends. Relays latest applied research relevant to OSDs. Provides “how to” information for the latest techniques in formulation/excipients, tablet manufacturing, capsule filling and other aspects of the process—including logistics like supply-chain management.
There’s no universally agreed definition of what constitutes a highly potent API (HPAPI). But a health-based exposure limit (HBEL) can serve as a more reliable indicator of whether an API is potent or...
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I have a confession to make: When I joined Tablets & Capsules in January 2022, I’m pretty sure I’d never heard the word “excipient”. If I had, I certainly couldn’t define it nor could I use it in a ...
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Pharma manufacturing raises dust in many steps—in the handling of bulk materials, to milling, granulating, tableting, encapsulating, coating, and even packaging. And yet, if you work in maintenance, ...
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Many chemical and pharmaceutical process engineers are challenged by metered dispensing of reactive powders into reactors and large tanks. But dispensing difficult to-handle ingredients in a contained...
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If you manufacture oral solid dosage drugs, your plant is likely full of a variety of bulk powders. Many of these powders are combustible, and if they accumulate, they can provide fuel for a ...
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Capsules are perceived as elegant, easy to swallow dosage forms, widely used for delivery of nutraceutical and medicinal preparations. Advances in capsule technologies have hugely facilitated the ...
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Minitablets, defined as solid dosage forms with a diameter below or equal to 3 mm, have many benefits: they are easy to swallow, offer uniform release kinetics, and are easy on the gastrointestinal ...
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Pharma execs generally consider cosmetic tablet coating a less essential aspect of manufacturing because cosmetic coatings typically do not affect the drug delivery. Perhaps they should reconsider; ...
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To the average consumer, one gelatin capsule looks pretty much like any other— give or take minor differences in shape, size or color. But, to an expert, this couldn’t be further from the truth. The ...
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When it comes to mixing nutraceutical ingredients, not all blenders are created equal. Because there’s a wide range of particles in each “mix”—of different sizes and bulk densities—getting the right ...
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Pharmaceuticals that begin development based on powders or refined by powders include gels, ointments and suspensions, or tablet coatings. For these products, many different powders and powder ...
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According to its Wikipedia entry: “Deadliest Catch is an American reality television series that premiered on the Discovery Channel on April 12, 2005. The show follows crab fishermen aboard fishing ...
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The fast-paced, highly regulated pharmaceutical industry requires companies to have a well-trained and competent workforce. Traditional training methods with their “read and understood” and formal ...
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LNK International Inc. recently selected Thomas Processing’s CTC continuous coaters to boost and modernize its plants in Hauppauge, New York. In this Q&A, David Bergen discusses the business reasons ...
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As consumer demand for natural and recognizable ingredients in tablet and capsule nutritional supplements increases, manufacturers are actively seeking ingredients
that will enable efficient ...
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