Delves into all aspects of R&D and manufacturing of all oral solid dose (OSD) forms. Tracks industry trends. Relays latest applied research relevant to OSDs. Provides “how to” information for the latest techniques in formulation/excipients, tablet manufacturing, capsule filling and other aspects of the process—including logistics like supply-chain management.
A tablet press forms pharmaceutical or nutraceutical tablets by compressing a powder or granular formulation between two steel punches within a hole bored into a steel die. A typical tablet consists ...
read more
Oral controlled-release (OCR) drug products release the active pharmaceutical ingredient (API) into the patient’s gastrointestinal (GI) tract either slowly or after a delay. This results in much of ...
read more
Innovative new drug molecules and technologies have paved the way for promising new therapies to some of the most pressing, life-threatening diseases. The FDA has affirmed that potential by granting ...
read more
A significant part of the global population—particularly geriatric, pediatric, and psychiatric patients—has difficulty swallowing solid oral dosage forms (SODFs). Approximately 40 to 60 percent of ...
read more
When lecturing at pharmaceutical R&D departments and colleges of pharmacy, I am often asked why one batch of a tablet formulation will compress differently from the previous batches. Often, the answer...
read more
A properly-designed dust collection system is a dietary supplement manufacturer’s best defense against cross-contamination, dust accumulation on surfaces, dust explosions and fires, and harm to plant ...
read more
The growing consumer interest in healthy living and natural products has led to an increase in nutraceutical production on a global scale, with market reports projecting that the global nutraceuticals...
read more
Continuous manufacturing of pharmaceutical finished products is now a reality. At this time, pharmaceutical companies are using continuous processes to manufacture four drug products licensed in the ...
read more
The tablet is the most popular dosage form for prescribed and over-the-counter medications. Tablets are a simple and convenient way to accurately dose active pharmaceutical ingredients and are ...
read more
Titanium dioxide (TiO2) has safely been used as a pigment in thousands of food and drug products all over the world for more than fifty years. Known in Europe and many other parts of the world as E171...
read more
Concern about microplastics has been growing for some time, particularly in Europe. Historically, microplastics contamination of the marine environment has been attributed to factors such as large ...
read more
To succeed in today’s demanding pharmaceutical manufacturing environment, a tablet coating process must be as efficient as possible. This means that each step or aspect of the coating process must be ...
read more
Film-coating technology has undergone a steady evolution over the last half century. At the beginning, film coating was limited to some extent by the need to rely on the use of organic solvents. ...
read more
About 80 percent of US consumers want to know which ingredients are in the products they consume, according to the 2018 Supplements/OTC/Rx Trends Database (SORD) report . Additionally, a survey ...
read more
In May 2016, the FDA published two final rules about nutrition labeling, one focused on revisions to food and supplement nutrition labeling requirements (21 CFR 101.9 and 101.36) [1, 2], and the other...
read more