Delves into all aspects of R&D and manufacturing of all oral solid dose (OSD) forms. Tracks industry trends. Relays latest applied research relevant to OSDs. Provides “how to” information for the latest techniques in formulation/excipients, tablet manufacturing, capsule filling and other aspects of the process—including logistics like supply-chain management.
Drug product developers carefully select excipients based on their function during the manufacturing process or in the final dosage form. Each ingredient must be present in the correct amount to ...
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The establishment of specifications for raw materials, in-process materials, and finished products is one of the essential regulatory requirements of current good manufacturing practices (cGMPs) for ...
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Continuous direct compression (CDC) tableting offers several key technical and process advantages over traditional batch tableting processes. First and foremost, it allows the manufacturer to develop ...
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The Tableting Specification Manual (TSM), published by the American Pharmacists Association (APhA), is the authoritative reference for tablet and tablet tooling specifications in North America.
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Encountering dissolution problems
during scale-up of a tablet
product can be frustrating and lead
to a costly delay in the product’s
time to market. However, a careful
investigation of the ...
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Cannabidiol (CBD) is a chemical compound derived from the cannabis plant. Now that CBD is legal in many states and is informally available through the internet, products that contain CBD are in high ...
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Sustainability has been a hot topic in the packaging industry and, if models are to be believed, will continue to be so in the future. The global market for sustainable packaging (also known as green ...
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Pharmaceutical manufacturers are increasingly developing new medicines that use highly potent active pharmaceutical ingredients (HPAPIs) and face a growing need for containment solutions that enable ...
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Although traditional batch processing has long been the norm in the pharmaceutical industry, drug product manufacturers have begun to shift toward continuous manufacturing as a more sustainable, ...
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Solid dosage manufacturers and contract packagers typically consider automating manual operations when significant, immediate problems are causing line downtime or when they can no longer tolerate an ...
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A minitablet is generally a round tablet with a flat or slightly convex face and a diameter between 1.0 and 3.0 millimeters. Minitablets are usually filled into a capsule, but they are also ...
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Metrics Contract Services is the contract development and manufacturing (CDMO) division of Mayne Pharma. In 2018, the CDMO opened a new 126,000-square-foot solid dosage manufacturing plant at its ...
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The final step before packaging a softgel product is to clean and polish the capsules to remove any residue. This residue may include lubricants such as mineral oil or MCT oil and leaked fill ...
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Surepharm is a contract manufacturing organization (CMO) located near Burton on Trent in the UK. The company has been in business for more than 25 years and specializes in solid dosage generic ...
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Currently, about two-thirds of all prescription drug products are solid dosage forms. Many of these products provide a combination of immediate and extended or delayed release of one or more active ...
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