Delves into all aspects of R&D and manufacturing of all oral solid dose (OSD) forms. Tracks industry trends. Relays latest applied research relevant to OSDs. Provides “how to” information for the latest techniques in formulation/excipients, tablet manufacturing, capsule filling and other aspects of the process—including logistics like supply-chain management.
Liquid-filled capsules are no longer a specialized workaround but a technically sophisticated platform that demands deliberate alignment among formulation design, manufacturing capability and quality ...
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Advances in technologies, data, and development strategies are reshaping how oral solid dosage drugs are designed and manufactured, with a clear emphasis on lowering cost, shortening timelines, and ...
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X-ray powder diffraction provides a window into the crystalline structure, enabling developers to identify and quantify phases with precision.
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Recent developments could significantly affect capsule sourcing and pricing for U.S. buyers and manufacturers.
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One element that is sometimes overlooked is data integrity from in vivo testing. Specifically, is data garnered from stressed species valid and/or reliable? Is it reproducible?
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Much like the winemakers who learned to harness pressure rather than fear it, OSD manufacturers are leveraging advances in manufacturing processes, formulation science, excipients and packaging ...
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As the industry looks toward 2026, oral solid dosage forms remain firmly at the center of pharmaceutical and nutraceutical innovation — but the forces shaping the market are becoming more complex and ...
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Tablet delamination and capping are the most common tablet defects, causing costly production disruptions and lost batches.
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Just as traveling salesmen once had to balance opportunity, risk and proximity to their customers, today’s pharmaceutical suppliers face similar pressures as they pursue the dream of the world’s ...
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Conventional drying will remain useful, but it does not have to set the limits of formulation. Lyophilization offers a way to reduce risk, protect value and build products that are ready today — and ...
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Driven by persistent supply chain disruptions, shifting trade dynamics, evolving customer expectations and the accelerating growth of the nutraceutical sector, the pharma ecosystem is rewiring where —...
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Although not a routine manufacturing step, granulation plays a central role in determining the quality, consistency and performance of modern OSD products. This article explores how granulation can ...
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Scaling up a tablet coating process from work performed with a small-scale unit to a full-scale production plant raises critical questions: Which controls and product attributes must remain unchanged,...
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Ensuring the quality of finished products not only requires in-house quality control processes but also a robust supplier qualification process. Establishing a supplier qualification program is one of...
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The FDA deadline to meet nitrosamine control guidance is upon us. Here’s a review of past nitrosamine-related regulatory actions — and lessons learned.
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