Delves into all aspects of R&D and manufacturing of all oral solid dose (OSD) forms. Tracks industry trends. Relays latest applied research relevant to OSDs. Provides “how to” information for the latest techniques in formulation/excipients, tablet manufacturing, capsule filling and other aspects of the process—including logistics like supply-chain management.
Solid oral dosage forms (SODFs), including tablets, capsules, and sachets, make up roughly 60 percent of the total pharmaceutical products market. Despite the development of new liquid biologics and ...
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Aqueous film coatings can enhance the appearance, stability, swallowability, and brand identity of pharmaceutical tablets. Coatings can also be used to mask the taste of a bitter or otherwise ...
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Dietary supplement consumers want products that are convenient and easy to administer, and research shows that capsules remain the preferred dosage form for 42 percent of US consumers thanks to their ...
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In the pharmaceutical industry, a detailed understanding of the impact of raw material variation on a drug product’s performance and manufacturing is key. Drug products consist of an active ...
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Compressed tablets continue to be the most popular pharmaceutical dosage form. They provide higher content uniformity and are easier to administer at home than syrups or suspensions. They also provide...
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A systematic approach to solving encapsulation problems caused by a sticky formulation capsule filling This article provides a best-practices approach to troubleshooting capsule-filling problems when ...
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Soft capsules, also called softgels, are one of the most widely used solid oral dosage forms, particularly in the nutraceutical market. Traditional softgels are made from gelatin, but interest in ...
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Annex 15 of the “EU Guidelines for Good Manufacturing Practice for Medicinal Products for Human and Veterinary Use” defines “change control” as: “A formal system by which qualified representatives of ...
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Recro Gainesville is a contract development and manufacturing organization (CDMO) that provides oral solid dosage (OSD) form development, regulatory support, clinical and commercial manufacturing, and...
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Pharmaceutical and nutraceutical manufacturers are increasingly seeking natural materials to encapsulate active ingredients.
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There was a time, decades ago, when I could’ve recited the location of nearly every empty-capsule manufacturing plant in the world. These days, I discover new suppliers of empty capsules at a ...
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Coenzyme Q10 (CoQ10) is an effective antioxidant that plays a fundamental role in cellular bioenergetics, offers cardiac health benefits, and prevents cell damage from free radicals. However, many ...
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Poorly joined hard-shell capsules are both visually unappealing and have the potential to leak. A leaking capsule will not have the appropriate fill weight, and its contents may spill onto other ...
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Recently, a Phase I immediate-release solid oral dosage formulation of a pro-drug in gelatin capsules failed to completely dissolve during a three-month accelerated stability study. Scientists at ...
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About 90 percent of API molecules in the discovery pipeline are water insoluble, contributing to bioavailability challenges.
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