Delves into all aspects of R&D and manufacturing of all oral solid dose (OSD) forms. Tracks industry trends. Relays latest applied research relevant to OSDs. Provides “how to” information for the latest techniques in formulation/excipients, tablet manufacturing, capsule filling and other aspects of the process—including logistics like supply-chain management.
During a webinar about capsule filling last year, I asked attendees to choose the most prevalent problem they faced operating their capsule filling process. As Figure 1 shows, the audience—comprising ...
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In pharmaceutical applications, CT can help fast-track new product and process development and assess the characteristics of existing products. Tablets and capsules, for example, can be CT-scanned ...
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As pharmaceutical manufacturers seek to fill dwindling pipelines, they are developing new chemistries that are sometimes difficult to stabilize over the desired shelf life. Traditional moisture ...
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The people who formulate and design tablets focus on engineering factors, but the organoleptic aspects were given little if any consideration. Yet organoleptic factors are the key to obtain a positive...
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After tablets, hard capsules are the pharmaceutical industry’s most widely used dosage delivery method. Most capsules are made of gelatin or hypromellose (hydroxypropyl methylcellulose, or HPMC), and ...
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On November 19 last year, the FDA issued public notifications informing consumers that 10 “natural” weight-loss and sexual-enhancement products contained undeclared active pharmaceutical ingredients (...
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Liquid fills can deliver active pharmaceutical ingredients (APIs) that are otherwise difficult or impossible to deliver via other solid dosage forms. That has led many research and development ...
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Capsules have come a long way since they were patented in 1834. Today they are one of the most common and popular means of orally administering pharmaceuticals and dietary supplements. Valued at $1.5 ...
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Manufacturers face several challenges when compressing nutraceutical tablets, many of which are unrefined natural ingredients that are abrasive, corrosive, and/or coarse. It’s thus important to ...
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Over the last two decades, many researchers have sought a better understanding of high-shear granulation. Some have even worked toward finding ways to predict the results of the process, which can ...
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Many of the early papers that addressed capsules made from hydroxypropyl methylcellulose (HPMC), or hypromellose, stated that they didn’t lose their mechanical properties with a reduction in moisture ...
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While high-profile CROs, CMOs, and CDMOs consolidate and grow, a cadre of individual consultants soldier on. Tablets & Capsules spoke with several of them about their work.
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Never have so many drug delivery systems based on hard capsules been available to pharmaceutical manufacturers and physicians. Today, they can choose from a variety of options to achieve immediate, ...
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Since 1820, the US Pharmacopeial Convention (United States Pharmacopeia, or USP) has published drug standards used in the USA and in more than 140 countries. Additionally, USP produces and supplies ...
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When I began organizing CDMOs into a nonprofit trade association three years ago, I didn’t expect that my short-form response to, “What do you do for a living?” would be, “I’m a lobbyist for the ...
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